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On 5 August, Alkarama sent an urgent appeal to the United Nations Working Group on Enforced or Involuntary Disappearances (WGEID) regarding the disappearances of Mahmoud Saleh Mohammed Ali and Hassan Saleh Ahmed Mohammed respectively arrested by Egyptian security and police forces on 7 June and 5 July 2015.

On 5 August 2015, Alkarama called upon the United Nations Working Group on Arbitrary Detention (WGAD) to intervene with the Egyptian authorities regarding the sentencing by Ismailia Military Court of Seif Al Islam Osama Shousha, a 16-year-old boy, to three years in prison and a 50,000 Egyptian pounds fine on 4 August.

On 22 July 2015, Alkarama sent an urgent appeal to the United Nations Working Group on Arbitrary Detention (WGAD) regarding the continuous detention of Esraa Mahfouz Mohamed El Taweel, a 23-year-old student who has been detained arbitrarily since her arrest on 1 June 2015.

On 20 July 2015, Alkarama sent an urgent appeal to the United Nations Working Group on Enforced or Involuntary Disappearances (WGEID) regarding the case of Mahmoud Tawfik Abdalaal, a 55-year-old former parliamentarian of the Freedom and Justice Party (FJP) – the political wing of the Muslim Brotherhood – disappeared since his arrest on 6 June 2015.

On 15 July 2015, Alkarama informed the United Nations Special Rapporteur on the promotion and protection of the right to freedom of opinion and expression (SR FRDX) of the expulsion, by the Egyptian authorities, of a 22-year-old French student, Fanny Ohier.

On 28 April 2015, following an urgent appeal sent by Alkarama on 8 January 2015, the United Nations Working Group on Arbitrary Detention (WGAD) issued an Opinion regarding the detention of 16-year-old Egyptian high school student,

On 10 July 2015, Alkarama sent an urgent appeal to the United Nations Working Group on Enforced of Involuntary Disappearances (WGEID) regarding the disappearances of four young men who disappeared following their abduction by members of the police and the army between 22 April and 28 May 2015.

On 7 July 2015, Alkarama sent a letter to the United Nations Special Rapporteur on the promotion and protection of human rights and fundamental freedoms while countering terrorism (SRCT) to ask the Egyptian authorities to refrain from adopting a new draft anti-terrorism law. Approved both by the Cabinet and the Supreme Judicial Council on 5 July 2015, this draft law is awaiting ratification by the President of the Republic.

On 16 June 2015, the Cairo Criminal Court confirmed the death sentences of Mohamed Morsi and several other Muslim Brotherhood leaders that had been handed in May 2015 and subsequently reviewed by the Grand Mufti of Egypt. On the same day, Morsi and 35 other defendants were also sentenced to life in prison under charges of espionage.

On 17 June 2015, Alkarama sent an urgent appeal to the United Nations Working Group on Enforced or Involuntary Disappearances (WGEID) regarding the cases of 54-year-old veterinarian, Dr Salah Attia Mohamed Fiki, and his son, a 20-year-old medicine student, Osama Salah Attia Mohamed Fiki – still a child under Egyptian law – both disappeared since their unlawful arrest by the Egyptian Security Forces on 23 April 2015.