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On 10 April 2015, Alkarama sent an urgent appeal to the United Nations Working on Enforced or Involuntary Disappearances (WGEID) regarding the disappearances of four Egyptian citizens in late 2014 and early 2015, because of their alleged affiliation with the Muslim Brotherhood, a socio-political movement that continues to be the subject of a violent repression from the authorities.

On 8 April 2015, Alkarama sent an urgent appeal to the United Nations Special Rapporteur on extrajudicial, arbitrary and summary executions (SR SUMX), regarding the imminent execution of six Egyptian citizens sentenced to death for crime they could not have committed since they were secretly detained in the infamous Azouli military prison when the events occurred.

On 2 April 2015, Alkarama sent an urgent appeal to United Nations Special Rapporteur on Torture (SRT) regarding the case of Mohammed Ali Hassan, a 31 year-old Egyptian journalist working for Egyptian News Network (ENN). He has been subjected to various acts of torture since his arrest in December 2014 and is currently on an open-ended hunger strike, putting his life at risk.

On 6 March 2015, the United Nations Special Rapporteur on Torture (SRT), Juan E.

On 24 March 2015, Alkarama sent an appeal to United Nations Special Rapporteur on Torture (SRT) regarding the case of Ammar Mohammed Mohammed Mahmoud, a 19 year-old Egyptian student who has been subjected to various acts of torture since his arrest in November 2014. Detained in deplorable conditions inside Tora prison, Ammar remains at high risk of torture and has not been brought before a judge yet.

On 20 March 2015, the Human Rights Council (HRC) adopted the outcome of Egypt's Universal Periodic Review (UPR), a process aimed at reviewing the human rights record of all UN Member States by every four years. In a context of serious and gross human rights violations in the country, the Egyptian authorities have accepted many of the HRC's recommendations regarding civil and political rights as well as economic, social and cultural ones.

On 12 March 2015, Alkarama sent an urgent appeal to the United Nations Working Group on Enforced Disappearances (WGEID) regarding the enforced disappearances of Ibrahim Ahmed Shaker, aged 20, Serag Eldin Ali Awad Abdel Mawla, 17, Metwally Abou Al Majd Suleiman Mohamed, 45 and his son Hisham Metwally Abou Al Majd Mohamed, 18.

On 7 March 2015, the Egyptian authorities carried out their first execution since Morsi's ouster in July 2013, despite Alkarama's urgent appeal to the United Nations Special Rapporteur on Extrajudicial, Summary or Arbitrary Executions (SUMX) asking the authorities to halt the execution. Mahmoud Hassan Ramadan Abdelnaby Negm was sentenced to death on 16 May 2014 following an unfair trial conducted by Alexandria's Criminal Court who admitted as evidence the confessions Hassan obtained under torture.

On 4 March 2015, Alkarama called on the United Nations Special Rapporteur on Summary Executions (SUMX) regarding the arbitrary executions of seven civilians during the Egyptian military operation on the Eastern Libyan coastal city of Derna on 16 February 2015. Amongst the victims were Rabha Saleh Ahmed Al Mansouri, 44, and three of her children, Afrah, 7, Huzaifa, 2 and Zakaria, 6. Only Mrs Al Mansouri's husband and their 8-year-old son survived the bombing of their house by the Egyptian army.

On 23 February 2015, Alkarama solicited the United Nations Special Rapporteur on Extrajudicial, Summary or Arbitrary Executions (SUMX) to ask the Egyptian authorities to launch investigations into the arbitrary executions of two men killed during military operations in North Sinai.